Peripheral artery disease (PAD) is the narrowing or blockage of blood vessels that run from the heart to other parts of the body. Smoking can cause PAD. Quit smoking to protect your Even nicotine free e cigarettes damage blood vessels E cigarette vapour could damage key blood vessels linked to heart disease, study warns The Independent The Independent Vaping: Not So Skin Safe? Effects on Ageing & Hydration Differential Effects of E Cigarette on Microvascular Endothelial Function, Arterial Stiffness and Oxidative Stress: A Randomized Crossover Trial Scientific Reports NIH funded studies show damaging effects of vaping, smoking on blood vessels National Institutes of Health (NIH)