Deleterious Effects of Reactive Metabolites Toxicology Rounds : Emergency Medicine News The Use and Potential Benefits of N Acetylcysteine in Non Acetaminophen Acute Liver Failure: An Etiology Based Review A quantum chemical study of the reactivity of acetaminophen (paracetamol) toxic metabolite N acetyl p benzoquinone imine with deoxyguanosine and glutathione ScienceDirect Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate Mechanisms of Adverse Drug Reactions Pharmacovigilance