Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Multiple pigmented lesions of the lower lip Journal of Oral and Maxillofacial Surgery An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Labial melanotic macule Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Multifocal pigmentation of the oral mucosa The Journal of the American Dental Association