Oral Melanotic Macule: Symptoms and Treatment Skinsight LABIAL LENTIGO, Labial Lentigo also called a labial melanotic macule, is a harmless, small, flat, brown spot on the lip. It can develop after repeated sun exposure. In most cases, labial lentigo Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Q Switched Laser for the treatment of mucocutaneous pigmentation on Peutz Jeghers Syndrome Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI