The role of glutathione S transferases in human disease pathogenesis and their current inhibitors ScienceDirect Is Mold Triggering Your Mast Cell Activation Syndrome? Olive leaf extract (OLE) reduces mast cell mediated allergic inflammation ScienceDirect Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Department of Pathology Lukacs Laboratory Frontiers Ironing out COPD: ferroptosis driven immune dysregulation, metabolic rewiring, and precision therapeutic opportunities