Glucose 6 phosphate dehydrogenase deficiency The Lancet Happy Week 6! Check out the graphic to learn more about Glutathione Synthetase Deficiency. Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Glutathione: What It Is, Why You Need It, How You Can Increase It The Amino Company Glutathione: pharmacological aspects and implications for clinical use Geriatric Care Glutathione synthetase deficiency MedLink Neurology