Discover Melanotan 1 vs 2 Differences Peptide Works Melanotan 2 results what results to expect Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and Melanotan 1 (10 MG) Sigma Compounds Peptides for tanning do exist. Melanotan 1 and Melanotan 2 both work at increasing melanin in the skin. Melanotan 1 takes longer to activate. Melnotan 1 is FDA approved. Melanotan 2 does libido, MELANOTAN 1 (10mg) stimulation of melanin synthesis.