NAPQI Wikipedia Paracetamol acetaminophen hepatotoxicity: new markers for monitoring the elimination of the reactive N Acetyl p benzoquinone imine bioRxiv ACETAMINOPHEN, SALICYLATES & NONSTEROIDAL ANTI INFLAMMATORY DRUGS Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body Acetaminophen & the kidney Renal Fellow Network GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY