Role of glutathione cycle and the pentose phosphate pathway in the Download Scientific Diagram The pentose phosphate pathway and cancer: Trends in Biochemical Sciences Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Pentose phosphate pathway: phases, reactions, & metabolic roles 15 Carbohydrates: Pentose Phosphate Pathway Basicmedical Key The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration Journal of Neuroinflammation Springer Nature Link