Melanotan 2 Oath Research Labial Macules: Dark Spots on the Lip Dermatology Advisor How to Get Rid of Labila Melanocytic Macule on Lips TikTok This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Dermoscopic Features of Mucosal Melanosis Semantic Scholar Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.