Spotty lips. These are labial melanotic macules, kinda like freckles on the lips. They are mostly due to age and sun exposure, but sometimes they run in families and are associated with Figure 1 from Oral melanotic macule a case report. Semantic Scholar COM Dec. 2011 Diagnosis UW School of Dentistry Labial melanotic macule Labial melanotic macule Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI