How to Check Your Genetic Data for G6PD Deficiency Department of Genetic Engineering @ SRM University: Genetic Awareness Program on Glucose 6 Phosphate Dehydrogenase Deficiency Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease Glucose 6 phosphate dehydrogenase (G6PD) deficiency: Video, Causes, & Meaning Osmosis G6PD Deficiency Causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are