The pentose phosphate pathway in health and disease Nature Metabolism Glucose 1 phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells: Molecular Cell Explain how Inactivity or absence of Glucose 6 phosphate dehydrogenase ; a rate limiting enzyme in the Pentose phosphate pathway could lead to oxidative stress.* HMP also known as the Pentose phosphate pathway. Consists of two irreversible oxidative rxs followed by a series of reversible The pentose phosphate pathway in health and disease Nature Metabolism Pentose Phosphate Pathway (PPP), Purine and Pyrimidine Metabolism Cell Biology, Genetics, and Biochemistry for Pre Clinical Students