Enhanced Sonodynamic Cancer Therapy through Boosting Reactive Oxygen Species and Depleting Glutathione Nano Letters Integrative Modeling of Oxidative Stress and C1 Metabolism Reveals Upregulation of Formaldehyde and Downregulation of Glutathione Noxious Cellular Injury Triggers an Oxidative Stress Gene Response Oxidative Stress and Cardiovascular Injury Circulation Identification of cytotoxic, glutathione reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion ScienceDirect Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification