Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists Oral Melanotic Macule: Symptoms and Treatment Skinsight A Black Spot on the Upper Gum for Many Years: Melanotic Macule Springer Nature Link COM Dec. 2011 Diagnosis UW School of Dentistry Removal of lip pigmentation with our Alma Q laser. Such lip spots (aka labial melanotic macules) appear for no apparent reason. Similar spots can appear due to smoking, sun damage, drug reactions, Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics