Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in Pigmented Lesions of the Oral Mucosa Springer Nature Link A collection of resources for RACGP exams Next Gen GP Text Book live webinars AKT and KFP questions Mucosal melanocytic macules This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.