Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( Taking L Carnitine with Semaglutide The Sanctuary Wellness Institute Dietary allicin reduces transformation of L carnitine to TMAO through impact on gut microbiota ScienceDirect Frontiers Gut microbiota dependant trimethylamine N oxide and hypertension Unraveling the Formation Mechanisms of Trimethylamine N Oxide and Its Inhibition by Food Ingredients: Toward Cardioprotective Food Development Journal of Agricultural and Food Chemistry TMAO metaorganismal pathway and chronic inflammatory diseases