Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Removal of lip pigmentation with our Alma Q laser. Such lip spots (aka labial melanotic macules) appear for no apparent reason. Similar spots can appear due to smoking, sun damage, drug reactions, Pigmented Lesions Springer Nature Link Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome Pigmented Lesions Pocket Dentistry