Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Dental Update Malignant oral melanoma: how to spot it and how it is managed Dental Update Oral melanotic macule" Peptide Dosing Schedule and Guidelines PDF Dose (Biochemistry) Chemistry Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360