At *therapeutic* doses, what is the primary metabolic pathway for acetaminophen (paracetamol)? Phase II conjugation (glucuronidation and sulfation) Phase I oxidation by CYP3A4 Phase I oxidation by CYP2E1 Direct excretion by the Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg kg intravenous acetaminophen in very preterm infants Pediatric Research Liver injury induced by paracetamol and challenges associated with intentional and unintentional use Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body Acetaminophen Use During Pregnancy and Neurodevelopmental Risk: Biological Plausibility1 Journal of Obstetrics and Gynaecology Canada