Pigmented lesions of the oral mucosa and perioral tissues: a flow chart for the diagnosis and some recommendations for the management Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Should I get a 2nd opinion about these freckles on my lips from another dermatologist? Last time they say it's just sun spots but the bottom one in particular still keeps me Clinical Challenge: Dark Lesion on Lower Lip MPR Melanotic Macule Lip TikTok Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Laser Lip Treatment for Lip Discoloration: Patient Transformation