FOXO regulation of TXNIP induces ferroptosis in satellite cells by inhibiting glutathione metabolism, promoting Sarcopenia Cellular and Molecular Life Sciences Springer Nature Link Olive leaf extract (OLE) reduces mast cell mediated allergic inflammation ScienceDirect A New Stage for Seasoned Actors Food Anaphylaxis and the Cysteinyl Leukotrienes New England Journal of Medicine IRE1 determines ferroptosis sensitivity through regulation of glutathione synthesis Nature Communications The Importance of Glutathione in Health and Healing Dr. Todd Maderis Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione.