Reminder of serious health risks with 'Melanotan 2' self tan products Irish Pharmacist What are the mechanism of action and side effects of Melanotan 2 (afamelanotide)? Avoid nasal tanning sprays or nasal tanners entirely. These products promise an all over tan without sun exposure but they are unregulated, can be unsafe, and contain potentially risky substances like Melanotan 2. Superpower Avoid nasal tanning sprays or nasal tanners entirely. These products can produce nasty side effects, such as nausea and vomiting, high blood pressure, respiratory issues, and even links to skin cancer. Nasal Melanotan II: Tanning injections, nasal sprays harmful to health