Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Pigmented Lesions of the Oral Mucosa Pocket Dentistry Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Does anyone know what this black mark on my lip is? Started last August so it's I've had it nearly a year, was living in Spain at the time for 6 months Taint melanotic of the lip vaporization laser UNILASER MDICA