G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics Glucose 6 Phosphate Dehydrogenase A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway Nature Chemical Biology Metabolism: The pentose phosphate pathway and G6PD deficiency (practice) Khan Academy File:Glutathion metabolism DE state in G6PD deficiency.png Wikimedia Commons